A Genetic Link between Morphogenesis and Cell Division during Formation of the Ventral Furrow in Drosophila

@article{Grosshans2000AGL,
  title={A Genetic Link between Morphogenesis and Cell Division during Formation of the Ventral Furrow in Drosophila},
  author={J{\"o}rg Grosshans and Eric F. Wieschaus},
  journal={Cell},
  year={2000},
  volume={101},
  pages={523-531}
}
Stages in development with rapid transitions between mitosis and morphogenesis may require specific mechanisms to coordinate cell shape change. Here we describe a novel mitotic inhibitor that acts during Drosophila gastrulation to counteract String/Cdc25, specifically in the cells that invaginate to form the mesoderm. We have identified two genes, frühstart… CONTINUE READING