A General Approach for Haplotype Phasing across the Full Spectrum of Relatedness

Abstract

Many existing cohorts contain a range of relatedness between genotyped individuals, either by design or by chance. Haplotype estimation in such cohorts is a central step in many downstream analyses. Using genotypes from six cohorts from isolated populations and two cohorts from non-isolated populations, we have investigated the performance of different… (More)
DOI: 10.1371/journal.pgen.1004234

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