A Gene Network Regulating Lysosomal Biogenesis and Function

@article{Sardiello2009AGN,
  title={A Gene Network Regulating Lysosomal Biogenesis and Function},
  author={M. Sardiello and M. Palmieri and Alberto di Ronza and D. Medina and M. Valenza and V. Gennarino and Chiara Di Malta and F. Donaudy and V. Embrione and R. Polishchuk and S. Banfi and G. Parenti and E. Cattaneo and A. Ballabio},
  journal={Science},
  year={2009},
  volume={325},
  pages={473 - 477}
}
Master Controller Cellular organelles allow the localized regulation of specialized processes. Under certain conditions, such as increased growth, organelles may be required to alter their function. Coordinated regulation of the gene networks required for mitochondrial and endoplasmic reticulum function has been observed. Now, Sardiello et al. (p. 473; published online 25 June) have discovered a gene network regulating the lysosome, the major organelle involved in the degradation of… Expand
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