A GWAS in uveal melanoma identifies risk polymorphisms in the CLPTM1L locus

Abstract

Uveal melanoma, a rare malignant tumor of the eye, is predominantly observed in populations of European ancestry. A genome-wide association study of 259 uveal melanoma patients compared to 401 controls all of European ancestry revealed a candidate locus at chromosome 5p15.33 (region rs421284: OR = 1.7, CI 1.43–2.05). This locus was replicated in an… (More)
DOI: 10.1038/s41525-017-0008-5

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