A GTPase Controlling Nuclear Trafficking: Running the Right Way or Walking RANdomly?

@article{Koepp1996AGC,
  title={A GTPase Controlling Nuclear Trafficking: Running the Right Way or Walking RANdomly?},
  author={Deanna M. Koepp and Pamela A. Silver},
  journal={Cell},
  year={1996},
  volume={87},
  pages={1-4}
}
In addition, certain GTP analogs inhibit nuclear import, indicating that GTP hydrolysis by Ran is neces-Macromolecular movement across the nuclear envelope sary for proper nuclear protein import. Failure by Ran is distinctly bidirectional. Proteins are targeted to and to hydrolyze and/or exchange nucleotide also results in enter the nucleus at nuclear pore complexes (NPCs) in a block in RNA export, providing a link between protein the nuclear envelope. The same NPCs promote passage and RNA… CONTINUE READING

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Proteins are targeted to and to hydrolyze and/or exchange nucleotide also results in enter the nucleus at nuclear pore complexes ( NPCs ) in a block in RNA export , providing a link between protein the nuclear envelope .
orchestration of these movements is essential for proper In a normal cell , Ran can be found in both the nucleus gene expression , DNA replication , RNA processing , and and the cytoplasm .
orchestration of these movements is essential for proper In a normal cell , Ran can be found in both the nucleus gene expression , DNA replication , RNA processing , and and the cytoplasm .
orchestration of these movements is essential for proper In a normal cell , Ran can be found in both the nucleus gene expression , DNA replication , RNA processing , and and the cytoplasm .
Nuclear EnvelopeDirect constitution part ofCell Nucleus
Proteins are targeted to and to hydrolyze and/or exchange nucleotide also results in enter the nucleus at nuclear pore complexes ( NPCs ) in a block in RNA export , providing a link between protein the nuclear envelope .
Nuclear EnvelopeAnatomic structure is physical part ofCell Nucleus
Proteins are targeted to and to hydrolyze and/or exchange nucleotide also results in enter the nucleus at nuclear pore complexes ( NPCs ) in a block in RNA export , providing a link between protein the nuclear envelope .
Proteins are targeted to and to hydrolyze and/or exchange nucleotide also results in enter the nucleus at nuclear pore complexes ( NPCs ) in a block in RNA export , providing a link between protein the nuclear envelope .
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