A GTP-binding protein of Escherichia coli has homology to yeast RAS proteins.

@article{Ahnn1986AGP,
  title={A GTP-binding protein of Escherichia coli has homology to yeast RAS proteins.},
  author={J. Ahnn and P. E. March and Howard Eugene Takiff and M. Inouye},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1986},
  volume={83 23},
  pages={8849-53}
}
The DNA sequence of a gene (era) located immediately downstream of the gene (rnc) encoding ribonuclease III of Escherichia coli was determined and found to encode a protein of 316 amino acid residues. The amino acid sequence of this protein, Era, has significant similarity to the yeast RAS proteins. Overexpression of the Era protein was achieved and GTP cross-linking experiments demonstrated that the protein was indeed capable of binding GTP, as are the yeast and mammalian ras gene products… CONTINUE READING

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