A GM-CSF/IL-3 fusion protein promotes neutrophil and platelet recovery in sublethally irradiated rhesus monkeys.

Abstract

The effects of a human GM-CSF/IL-3 fusion protein (PIXY321) were examined in a primate model of rebound hematopoiesis following sublethal irradiation. The results demonstrated an enhanced rate of both neutrophil and platelet regeneration, as well as functional activation of circulating neutrophils. 

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