A GGCAGG motif in minisatellites affecting their germline instability.

@article{Mitani1990AGM,
  title={A GGCAGG motif in minisatellites affecting their germline instability.},
  author={Kinuko Mitani and Yasuko Takahashi and R. Kominami},
  journal={The Journal of biological chemistry},
  year={1990},
  volume={265 25},
  pages={15203-10}
}
Mouse and human genomes contain hypervariable DNA regions consisting of tandem repeats of a short sequence referred to as minisatellites. This variation is thought to arise through processes such as unequal crossover or replication slippage. A mo-1 minisatellite probe comprising a 14-base pair repeat sequence reveals many polymorphic fragments even in DNA of BALB/c sublines. Oligonucleotide probes with single base substitution in the mo-1 have been synthesized and used for assessing sequence… CONTINUE READING
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