A GAL4-driver line resource for Drosophila neurobiology.

  title={A GAL4-driver line resource for Drosophila neurobiology.},
  author={Arnim Jenett and G. Rubin and T. B. Ngo and D. Shepherd and C. Murphy and H. Dionne and B. Pfeiffer and A. Cavallaro and D. Hall and J. Jeter and Nirmala Iyer and Dona Fetter and Joanna H Hausenfluck and H. Peng and Eric T. Trautman and R. Svirskas and E. Myers and Zbigniew R Iwinski and Y. Aso and Gina M. Depasquale and Adrianne Enos and Phuson Hulamm and Shing Chun Benny Lam and Hsing-Hsi Li and T. Laverty and Fuhui Long and L. Qu and S. Murphy and K. Rokicki and Todd Safford and K. Shaw and J. Simpson and A. Sowell and S. Tae and Yang Yu and Christopher Zugates},
  journal={Cell reports},
  volume={2 4},
  • Arnim Jenett, G. Rubin, +33 authors Christopher Zugates
  • Published 2012
  • Biology, Medicine
  • Cell reports
  • We established a collection of 7,000 transgenic lines of Drosophila melanogaster. Expression of GAL4 in each line is controlled by a different, defined fragment of genomic DNA that serves as a transcriptional enhancer. We used confocal microscopy of dissected nervous systems to determine the expression patterns driven by each fragment in the adult brain and ventral nerve cord. We present image data on 6,650 lines. Using both manual and machine-assisted annotation, we describe the expression… CONTINUE READING
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