A Further TWEAK to Multiple Sclerosis Pathophysiology

@article{Nazeri2013AFT,
  title={A Further TWEAK to Multiple Sclerosis Pathophysiology},
  author={Arash Nazeri and Pouria Heydarpour and Shokufeh Sadaghiani and Mohammad Ali Sahraian and Linda Burkly and Amit Bar-Or},
  journal={Molecular Neurobiology},
  year={2013},
  volume={49},
  pages={78-87}
}
  • Arash Nazeri, Pouria Heydarpour, +3 authors Amit Bar-Or
  • Published in Molecular Neurobiology 2013
  • Medicine, Biology
  • Tumor necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK) is a member of the TNF super family that controls many cellular activities including proliferation, migration, differentiation, apoptosis, and inflammation by binding to fibroblast growth factor-inducible 14 (Fn14), a highly inducible cell surface receptor. Recent studies have indicated that TWEAK–Fn14 axis signaling may contribute to chronic autoimmune diseases. TWEAK expression via microglia in cortical lesions, presence of… CONTINUE READING

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