A Functional Role for Specific Spliced Variants of the α7β1 Integrin in Acetylcholine Receptor Clustering

Abstract

The clustering of acetylcholine receptors (AChR) on skeletal muscle fibers is an early event in the formation of neuromuscular junctions. Recent studies show that laminin as well as agrin can induce AChR clustering. Since the a 7 b 1 integrin is a major laminin receptor in skeletal muscle, we determined if this integrin participates in laminin and/or agrin… (More)

Topics

9 Figures and Tables