A Fully Self-Contained Logarithmic Closed-Loop Deep Brain Stimulation SoC With Wireless Telemetry and Wireless Power Management

@article{Rhew2014AFS,
  title={A Fully Self-Contained Logarithmic Closed-Loop Deep Brain Stimulation SoC With Wireless Telemetry and Wireless Power Management},
  author={Hyo-Gyuem Rhew and Jaehun Jeong and Jeffrey Fredenburg and Sunjay Dodani and Parag G. Patil and Michael P. Flynn},
  journal={IEEE Journal of Solid-State Circuits},
  year={2014},
  volume={49},
  pages={2213-2227}
}
Although closed-loop deep brain stimulation (DBS) promises treatment of many neurological disorders, an implantable system-on-chip (SoC) implementing an effective closed-loop DBS algorithm has not been demonstrated. This work introduces a logarithmic, closed-loop DBS system that detects and processes low-frequency brain field signals to control and adapt stimulation currents. The system records and processes neural signals with four low-noise neural amplifier (LNA) channels, a multiplexed… CONTINUE READING