A Fully Atomistic Model of the Cx32 Connexon

@article{Pantano2008AFA,
  title={A Fully Atomistic Model of the Cx32 Connexon},
  author={Sergio Pantano and Francesco Zonta and Fabio Mammano},
  journal={PLoS ONE},
  year={2008},
  volume={3},
  pages={183 - 192}
}
Connexins are plasma membrane proteins that associate in hexameric complexes to form channels named connexons. Two connexons in neighboring cells may dock to form a "gap junction" channel, i.e. an intercellular conduit that permits the direct exchange of solutes between the cytoplasm of adjacent cells and thus mediate cell-cell ion and metabolic signaling. The lack of high resolution data for connexon structures has hampered so far the study of the structure-function relationships that link… CONTINUE READING

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