A Free-Standing Homing Endonuclease Targets an Intron Insertion Site in the psbA Gene of Cyanophages

@article{Zeng2009AFH,
  title={A Free-Standing Homing Endonuclease Targets an Intron Insertion Site in the psbA Gene of Cyanophages},
  author={Qinglu Zeng and Richard P. Bonocora and David A. Shub},
  journal={Current Biology},
  year={2009},
  volume={19},
  pages={218-222}
}
Homing endonuclease genes are mobile elements that promote their duplication into cognate sites that lack the endonuclease gene [1, 2]. The homing endonuclease initiates this event through site-specific DNA cleavage. Copying of the endonuclease gene follows as a consequence of DNA repair. A genome containing a homing endonuclease gene is subject to self-cleavage. Protection is accomplished through DNA sequence polymorphisms, as is the case in intronless homing of free-standing endonuclease… CONTINUE READING
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