A Francisella virulence factor catalyses an essential reaction of biotin synthesis.

Abstract

We recently identified a gene (FTN_0818) required for Francisella virulence that seemed likely involved in biotin metabolism. However, the molecular function of this virulence determinant was unclear. Here we show that this protein named BioJ is the enzyme of the biotin biosynthesis pathway that determines the chain length of the biotin valeryl side-chain… (More)
DOI: 10.1111/mmi.12460

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