A Factor Preventing the Development of Lung Metastases in Rats with Sarcomas

@article{Proctor1973AFP,
  title={A Factor Preventing the Development of Lung Metastases in Rats with Sarcomas},
  author={John Proctor and C. M. Rudenstam and P. Hansen Alexander},
  journal={Nature},
  year={1973},
  volume={242},
  pages={29-31}
}
An immunologically specific factor circulating in lymph and blood prevents the occurrence of lung metastases in rats with sarcomas growing in the leg. Removal of thoracic duct lymph causes such tumours to metastasize to the lung. This is due to the removal of a plasma factor and not of lymphocytes. 
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