A Double-Blind Controlled Trial of S-1530 in Patients with Insomnia

@article{Ito1973ADC,
  title={A Double-Blind Controlled Trial of S-1530 in Patients with Insomnia},
  author={E. Ito and T. Matsui and T. Okada and H. Watanabe and Y. Nagata and A. Akutsu and Taikobo Onoda},
  journal={Rinsho Yakuri\/japanese Journal of Clinical Pharmacology and Therapeutics},
  year={1973},
  volume={4},
  pages={61-75}
}
  • E. Ito, T. Matsui, +4 authors Taikobo Onoda
  • Published 1973
  • Medicine
  • Rinsho Yakuri\/japanese Journal of Clinical Pharmacology and Therapeutics
  • In a controlled double-blind study the hypnotic effect of S-1530 (5 mg q.d. for 7 consecutive nights) was investigated in comparison with that of nitrazepam (5mg) and a matching placebo in a series of 156 insomniac patients divided into three groups. Twenty-one eventually dropped out, then data were analyzed for evidence of hypnotic efficacy.By the Kruskal-Wallis H-test, there was no evidence of significant difference in effectiveness of drugs among the three groups according to global… CONTINUE READING