A Diselenide turn-on Fluorescent Probe for the Detection of Thioredoxin Reductase.
@article{Mafireyi2020ADT,
title={A Diselenide turn-on Fluorescent Probe for the Detection of Thioredoxin Reductase.},
author={Tendai Mafireyi and Madeleine Laws and John W. Bassett and Pamela B. Cassidy and Jorge O. Escobedo and Robert M. Strongin},
journal={Angewandte Chemie},
year={2020},
url={https://api.semanticscholar.org/CorpusID:218873258}
}The first diselenide-based probe for the selective detection of thioredoxin reductase (TrxR), an enzyme commonly overexpressed in melanomas, is reported, showing improved signaling of TrxR activity compared to the disulfide analogue.
28 Citations
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