A Direct Aldol Addition of Simple Thioesters Employing Soft Enolization

@inproceedings{Zhou2007ADA,
  title={A Direct Aldol Addition of Simple Thioesters Employing Soft Enolization},
  author={Guoqiang Zhou and Julianne M. Yost and Don M Coltart},
  year={2007}
}
Simple thioesters undergo direct aldol addition to aldehydes in the presence of magnesium bromide-diethyl ether and N,N-diisopropylethylamine using untreated, reagent grade dichloromethane under atmospheric conditions. The reactions proceed extremely rapidly and in excellent yield.