A Digital Microfluidic Biosensor for Multianalyte Detection

  title={A Digital Microfluidic Biosensor for Multianalyte Detection},
  author={Vijay Srinivasan and Vamsee K. Pamula and Michael G. Pollack},
A microfluidic lab-on-chip (LoC) for measuring the concentration of human body metabolites, using submicroliter droplets as reaction chambers, is presented in this paper. The device is based on the manipulation of droplets using the principle of electrowetting and is integrated with an optical absorbance measurement system for detection. We have demonstrated the detection of glucose using a colorimetric enzyme-kinetic assay in less than 40 seconds. The sensor response is linear in the range of… CONTINUE READING
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To - wards digital microfluidic circuits : creating , transporting , cutting , and merging liquid droplets by electroweningbased actuation

  • S-K. Fan, H. Moon, C-J. Kim
  • 2002

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