A Defined Tuberculosis Vaccine Candidate Boosts BCG and Protects Against Multidrug-Resistant Mycobacterium tuberculosis

  title={A Defined Tuberculosis Vaccine Candidate Boosts BCG and Protects Against Multidrug-Resistant Mycobacterium tuberculosis},
  author={S. Bertholet and Gregory C. Ireton and D. Ordway and H. Windish and Samuel O. Pine and Maria Kahn and Tony Phan and I. Orme and T. Vedvick and S. Baldwin and R. Coler and S. Reed},
  journal={Science Translational Medicine},
  pages={53ra74 - 53ra74}
  • S. Bertholet, Gregory C. Ireton, +9 authors S. Reed
  • Published 2010
  • Medicine
  • Science Translational Medicine
  • A vaccine with a four-protein fusion peptide from Mycobacterium tuberculosis effectively boosts the current childhood TB vaccine and protects against drug-resistant TB. A Superior Shot for Tuberculosis Going to the doctor for routine “shots” is a dreaded childhood right of passage. The freedom from serious diseases—polio, smallpox, and diphtheria—clearly compensates for the pain. But one shot given in many countries (but not the United States)—bacillus Calmette-Guérin (BCG), a vaccine against… CONTINUE READING
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    • Submitted 22 March 2010 Accepted
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