A DNAzyme that walks processively and autonomously along a one-dimensional track.

@article{Tian2005ADT,
  title={A DNAzyme that walks processively and autonomously along a one-dimensional track.},
  author={Ye Tian and Yu He and Yi Liang Chen and Peng Yin and Chengde Mao},
  journal={Angewandte Chemie},
  year={2005},
  volume={44 28},
  pages={
          4355-8
        }
}
  • Ye Tian, Yu He, +2 authors Chengde Mao
  • Published 2005
  • Chemistry, Physics, Medicine
  • Angewandte Chemie
  • Herein, we report a DNA nanodevice that autonomously and processively moves along a DNA track. The motion mechanism of this DNA device is reminiscent of that of singleheaded myosins I, a family of cellular protein motors. The DNA device contains a DNA enzyme (DNAzyme) that constantly extracts chemical energy from its substrate molecules (RNA) and uses this energy to fuel the motion of the DNA device. Nanomachines have potential applications in smart materials, sensors, and optoelectronic… CONTINUE READING

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