A DNA vaccine directed against a rainbow trout rhabdovirus induces early protection against a nodavirus challenge in turbot.

@article{Sommerset2003ADV,
  title={A DNA vaccine directed against a rainbow trout rhabdovirus induces early protection against a nodavirus challenge in turbot.},
  author={Ingunn Sommerset and Ellen Lorenzen and Niels Lorenzen and Hogne Bleie and Audun Helge Nerland},
  journal={Vaccine},
  year={2003},
  volume={21 32},
  pages={4661-7}
}
A DNA vaccine encoding the envelope glycoprotein from a fish rhabdovirus, viral hemorrhagic septicemia virus (VHSV), has previously been shown to induce both early and long time protection against the virus in rainbow trout. Challenge experiments have revealed that the immunity established shortly after vaccination is cross-protective against heterologous fish rhabdoviruses. In this study, we show that the DNA vaccine encoding the VHSV glycoprotein also induces early protection against a non… CONTINUE READING
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