A DNA target of 30 bp is sufficient for RNA-directed DNA methylation.

@article{Plissier2000ADT,
  title={A DNA target of 30 bp is sufficient for RNA-directed DNA methylation.},
  author={Thiery P{\'e}lissier and Michael Wassenegger},
  journal={RNA},
  year={2000},
  volume={6 1},
  pages={55-65}
}
In higher plants, RNA-DNA interactions can trigger de novo methylation of genomic sequences via a process that is termed RNA-directed DNA methylation (RdDM). In potato spindle tuber viroid (PSTVd)-infected tobacco plants, this process can potentially lead to methylation of all C residues at symmetrical and nonsymmetrical sites within chromosomal inserts that consist of multimers of the 359-bp-long PSTVd cDNA. Using PSTVd cDNA subfragments, we found that genomic targets with as few as 30 nt of… CONTINUE READING

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