A DNA electrochemical sensor based on nanogold-modified poly-2,6-pyridinedicarboxylic acid film and detection of PAT gene fragment.

@article{Yang2007ADE,
  title={A DNA electrochemical sensor based on nanogold-modified poly-2,6-pyridinedicarboxylic acid film and detection of PAT gene fragment.},
  author={J. Yang and T. Yang and Yuanyuan Feng and K. Jiao},
  journal={Analytical biochemistry},
  year={2007},
  volume={365 1},
  pages={
          24-30
        }
}
A new DNA electrochemical biosensor is described for electrochemical impedance spectroscopy (EIS) detection of the sequence-specific DNA related to PAT transgene in the transgenic plants. Poly-2,6-pyridinedicarboxylic acid film (PDC) was fabricated by electropolymerizing 2,6-pyridinedicarboxylic acid on the glassy carbon electrode (GCE). The gold nanoparticles (NG) were modified on the PDC/GCE to prepare NG/PDC/GCE, and then DNA probe (ssDNA) was immobilized on the NG/PDC/GCE by the interaction… Expand
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