A DNA-conjugated magnetic nanoparticle assay for assessing genotoxicity.

@article{Medley2012ADM,
  title={A DNA-conjugated magnetic nanoparticle assay for assessing genotoxicity.},
  author={Colin D. Medley and Joshua E. Smith and Larry S Wigman and Nik P Chetwyn},
  journal={Analytical and bioanalytical chemistry},
  year={2012},
  volume={404 8},
  pages={2233-9}
}
The genotoxicity of a molecule refers to its ability to interact with DNA in a way that inhibits normal DNA replication and transcription possibly leading to mutagenesis or carcinogenesis. Assessing the genotoxicity of a compound is critical in the development of pharmaceuticals and other products designed for human consumption or use. Typically… CONTINUE READING