A D-Peptide Ligand of Integrins for Simultaneously Targeting Angiogenic Blood Vasculature and Glioma Cells.

Abstract

The current prognosis of glioma patients remains poor after intensive multimodal treatments, which is partially due to the existence of blood-brain tumor barrier (BBTB). In the present study, a novel "bifunctional ligand" (termed DVS) was developed by retro-inverso isomerization. DVS is a ligand of integrins highly expressed on glioma cells and tumor… (More)
DOI: 10.1021/acs.molpharmaceut.7b00944

Cite this paper

@article{Ren2017ADL, title={A D-Peptide Ligand of Integrins for Simultaneously Targeting Angiogenic Blood Vasculature and Glioma Cells.}, author={Yachao Ren and Changyou Zhan and Jie Gao and Mingfei Zhang and Xiaoli Wei and Man Ying and Zining Liu and Weiyue Lu}, journal={Molecular pharmaceutics}, year={2017} }