A Cytoplasmic Complex Mediates Specific mRNA Recognition and Localization in Yeast

@inproceedings{Mller2011ACC,
  title={A Cytoplasmic Complex Mediates Specific mRNA Recognition and Localization in Yeast},
  author={Marisa M{\"u}ller and Roland Gerhard Heym and Andreas Mayer and Katharina Kramer and Maria Schmid and Patrick Cramer and Henning Urlaub and Ralf-Peter Jansen and Dierk Niessing},
  booktitle={PLoS biology},
  year={2011}
}
In eukaryotes, hundreds of mRNAs are localized by specialized transport complexes. For localization, transcripts are recognized by RNA-binding proteins and incorporated into motor-containing messenger ribonucleoprotein particles (mRNPs). To date, the molecular assembly of such mRNPs is not well understood and most details on cargo specificity remain unresolved. We used ASH1-mRNA transport in yeast to provide a first assessment of where and how localizing mRNAs are specifically recognized and… CONTINUE READING

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