A Crucial Role for Forebrain Adenosine A2A Receptors in Amphetamine Sensitization

@article{Bastia2005ACR,
  title={A Crucial Role for Forebrain Adenosine A2A Receptors in Amphetamine Sensitization},
  author={Elena Bastia and Y Xu and Angela C. Scibelli and Yuan-Ji Day and Joel M Linden and Jiang-fan Chen and Michael A. Schwarzschild},
  journal={Neuropsychopharmacology},
  year={2005},
  volume={30},
  pages={891-900}
}
Adenosine A2A receptors (A2ARs) are well positioned to influence the maladaptive CNS responses to repeated dopaminergic stimulation in psychostimulant addiction. Expression of A2ARs in brain is largely restricted to the nucleus accumbens and striatum, where molecular adaptations mediate chronic effects of psychostimulants such as behavioral sensitization… CONTINUE READING