A Critical View on the Role of Migraine Triggers in the Genesis of Migraine Pain

  title={A Critical View on the Role of Migraine Triggers in the Genesis of Migraine Pain},
  author={Dan Levy and Andrew M. Strassman and Rami Burstein},
  journal={Headache: The Journal of Head and Face Pain},
A number of distinct endogenous and exogenous factors have been implicated in migraine precipitation but the exact nature of the triggering process itself and its relationship to the genesis of the headache remains largely speculative. In this article, we examine the potential sites and downstream cascades through which migraine triggers might exert their action to promote the activation of the migraine pain pathway. We further look at the laterality of the headache as a potential indicator for… 

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