A Critical Review of the Fluoroquinolones

  title={A Critical Review of the Fluoroquinolones},
  author={G. Zhanel and K. Ennis and L. Vercaigne and A. Walkty and A. Gin and J. Embil and H. Smith and D. Hoban},
  • G. Zhanel, K. Ennis, +5 authors D. Hoban
  • Published 2002
  • Medicine
  • Drugs
  • The new fluoroquinolones (clinafloxacin, gatifloxacin, gemifloxacin, grepafloxacin, levofloxacin, moxifloxacin, sitafloxacin, sparfloxacin and trovafloxacin) offer excellent activity against Gram-negative bacilli and improved Gram-positive activity (e.g. against Streptococcus pneumoniae and Staphylococcus aureus) over ciprofloxacin. Ciprofloxacin still maintains the best in vitro activity against Pseudomonas aeruginosa. Clinafloxacin, gatifloxacin, moxifloxacin, sitafloxacin, sparfloxacin and… CONTINUE READING
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