A Critical Review of Magnetic Resonance Spectroscopy Studies of Obsessive-Compulsive Disorder

  title={A Critical Review of Magnetic Resonance Spectroscopy Studies of Obsessive-Compulsive Disorder},
  author={Brian P Brennan and Scott L. Rauch and J. Eric Jensen and Harrison Graham Pope},
  journal={Biological Psychiatry},
Functional neuroimaging studies have converged to suggest that cortico-striatal-thalamo-cortical (CSTC) circuit dysfunction is a core pathophysiologic feature of obsessive-compulsive disorder (OCD). Now, complementary approaches examining regional neurochemistry are beginning to yield additional insights with regard to the neurobiology of aberrant CSTC circuitry in OCD. In particular, proton magnetic resonance spectroscopy, which allows for the in vivo quantification of various neurochemicals… CONTINUE READING
Highly Cited
This paper has 57 citations. REVIEW CITATIONS
Related Discussions
This paper has been referenced on Twitter 8 times. VIEW TWEETS


Publications citing this paper.
Showing 1-10 of 23 extracted citations

Glutamate Genetics in Obsessive-Compulsive Disorder: A Review.

Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent • 2017
View 1 Excerpt

Biological markers for anxiety disorders, OCD and PTSD - a consensus statement. Part I: Neuroimaging and genetics.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry • 2016

57 Citations

Citations per Year
Semantic Scholar estimates that this publication has 57 citations based on the available data.

See our FAQ for additional information.