A Critical Review of Magnetic Resonance Spectroscopy Studies of Obsessive-Compulsive Disorder

@article{Brennan2013ACR,
  title={A Critical Review of Magnetic Resonance Spectroscopy Studies of Obsessive-Compulsive Disorder},
  author={Brian P Brennan and Scott L. Rauch and J. Eric Jensen and Harrison Graham Pope},
  journal={Biological Psychiatry},
  year={2013},
  volume={73},
  pages={24-31}
}
Functional neuroimaging studies have converged to suggest that cortico-striatal-thalamo-cortical (CSTC) circuit dysfunction is a core pathophysiologic feature of obsessive-compulsive disorder (OCD). Now, complementary approaches examining regional neurochemistry are beginning to yield additional insights with regard to the neurobiology of aberrant CSTC circuitry in OCD. In particular, proton magnetic resonance spectroscopy, which allows for the in vivo quantification of various neurochemicals… CONTINUE READING
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