A Controlled-Release Drug Delivery System on a Chip Using Electrolysis

@article{Huang2012ACD,
  title={A Controlled-Release Drug Delivery System on a Chip Using Electrolysis},
  author={Pen-Li Huang and Po-Hung Kuo and Yu-Jie Huang and Hsin-Hung Liao and Y.-J. J. Yang and Tao Wang and Yao-Hong Wang and Shey-Shi Lu},
  journal={IEEE Transactions on Industrial Electronics},
  year={2012},
  volume={59},
  pages={1578-1587}
}
A system-on-a-chip (SOC) with integrated drug reservoirs for drug delivery is proposed. Electrolysis is used to generate microbubbles, which are employed as a force to open the reservoirs and release the drug. Wireless components, including an on/off keying receiver, microcontrol unit, regulator, clock divider, and power-on reset, are integrated for remote drug activation. The proposed microchip is fabricated by Taiwan Semiconductor Manufacturing Company 0.35-μm CMOS technology followed by post… CONTINUE READING

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