A Computational Hypothesis for Allostasis: Delineation of Substance Dependence, Conventional Therapies, and Alternative Treatments

@inproceedings{Levy2013ACH,
  title={A Computational Hypothesis for Allostasis: Delineation of Substance Dependence, Conventional Therapies, and Alternative Treatments},
  author={Yariv Z. Levy and Dino J Levy and Andrew G. Barto and Jerrold S. Meyer},
  booktitle={Front. Psychiatry},
  year={2013}
}
The allostatic theory of drug abuse describes the brain's reward system alterations as substance misuse progresses. Neural adaptations arising from the reward system itself and from the antireward system provide the subject with functional stability, while affecting the person's mood. We propose a computational hypothesis describing how a virtual subject's drug consumption, cognitive substrate, and mood interface with reward and antireward systems. Reward system adaptations are assumed… CONTINUE READING