A Complex of Equine Lysozyme and Oleic Acid with Bactericidal Activity against Streptococcus pneumoniae

@inproceedings{Clementi2013ACO,
  title={A Complex of Equine Lysozyme and Oleic Acid with Bactericidal Activity against Streptococcus pneumoniae},
  author={Emily A. Clementi and Kristina R. Wilhelm and J{\"u}rgen Schleucher and Ludmilla A Morozova-Roche and Anders P H{\aa}kansson},
  booktitle={PloS one},
  year={2013}
}
HAMLET and ELOA are complexes consisting of oleic acid and two homologous, yet functionally different, proteins with cytotoxic activities against mammalian cells, with HAMLET showing higher tumor cells specificity, possibly due to the difference in propensity for oleic acid binding, as HAMLET binds 5-8 oleic acid molecules per protein molecule and ELOA binds 11-48 oleic acids. HAMLET has been shown to possess bactericidal activity against a number of bacterial species, particularly those with a… CONTINUE READING