A Complex-based Reconstruction of the Saccharomyces cerevisiae Interactome *S⃞

  title={A Complex-based Reconstruction of the Saccharomyces cerevisiae Interactome *S⃞},
  author={Haidong Wang and Boyko Kakaradov and Sean R. Collins and Lena Karotki and Dorothea Fiedler and Michael Shales and Kevan M. Shokat and Tobias C. Walther and Nevan J. Krogan and Daphne Koller},
  journal={Molecular & Cellular Proteomics : MCP},
  pages={1361 - 1381}
Most cellular processes are performed by proteomic units that interact with each other. These units are often stoichiometrically stable complexes comprised of several proteins. To obtain a faithful view of the protein interactome we must view it in terms of these basic units (complexes and proteins) and the interactions between them. This study makes two contributions toward this goal. First, it provides a new algorithm for reconstruction of stable complexes from a variety of heterogeneous… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 45 extracted citations


Publications referenced by this paper.
Showing 1-10 of 93 references

Large-scale mapping of human protein–protein interactions by mass spectrometry

Molecular systems biology • 2007
View 17 Excerpts
Highly Influenced

An efficient algorithm for large-scale detection of protein families

A. J. Enright, S. Van Dongen, C. A. Ouzounis
Nucleic Acids Res • 2002
View 12 Excerpts
Highly Influenced

Logistic regression, Ada

M. Collins, R. Schapire, Y. Singer
Boost and Bregman distances. Mach. Learn • 2002
View 6 Excerpts
Highly Influenced

DIP: the Database of Interacting Proteins

Nucleic Acids Research • 2000
View 5 Excerpts
Highly Influenced

The Stanford Microarray Database: data access and quality assessment tools

Nucleic Acids Research • 2003
View 4 Excerpts
Highly Influenced

SGD: Saccharomyces Genome Database

Nucleic Acids Research • 1998
View 7 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…