A Comparison of Vascular Effects from Complex and Individual Air Pollutants Indicates a Role for Monoxide Gases and Volatile Hydrocarbons

@inproceedings{Campen2010ACO,
  title={A Comparison of Vascular Effects from Complex and Individual Air Pollutants Indicates a Role for Monoxide Gases and Volatile Hydrocarbons},
  author={M. Campen and Amie K. Lund and Melanie L. Doyle-Eisele and Jacob D Mcdonald and Travis L. Knuckles and Annette C. Rohr and Eladio M. Knipping and Joe L. Mauderly},
  booktitle={Environmental health perspectives},
  year={2010}
}
BACKGROUND Emerging evidence suggests that the systemic vasculature may be a target of inhaled pollutants of vehicular origin. We have identified several murine markers of vascular toxicity that appear sensitive to inhalation exposures to combustion emissions. OBJECTIVE We sought to examine the relative impact of various pollutant atmospheres and specific individual components on these markers of altered vascular transcription and lipid peroxidation. METHODS Apolipoprotein E knockout (ApoE… CONTINUE READING