A Comparison of Three Bioinformatics Pipelines for the Analysis ofPreterm Gut Microbiota using 16S rRNA Gene Sequencing Data

@article{Plummer2015ACO,
  title={A Comparison of Three Bioinformatics Pipelines for the Analysis ofPreterm Gut Microbiota using 16S rRNA Gene Sequencing Data},
  author={Erica L. Plummer and Jimmy Twin and Dieter M Bulach and Susan Garl and Sepehr N. Tabrizi},
  journal={Journal of Proteomics \& Bioinformatics},
  year={2015},
  volume={8},
  pages={1-9}
}
Objective and Methods: Analysis of massive parallel sequencing 16S rRNA data requires the use of sophisticated bioinformatics pipelines. Several pipelines are available, however there is limited literature available comparing the features, advantages and disadvantages of each pipeline. This makes the choice of which method to use often unclear. Using gut microbial read data collected from a cohort of very preterm babies, we compared three pipelines commonly used for 16S rRNA gene analysis… Expand

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