A Comparison of Psychologic Responses to Ketamine and Thiopental–Nitrous Oxide–Halothane Anesthesia

  title={A Comparison of Psychologic Responses to Ketamine and Thiopental–Nitrous Oxide–Halothane Anesthesia},
  author={J M Garfield and Frances B. Garfield and J. Gilbert Stone and D. Hopkins and Lisa A. Johns},
Subjective psychologic responses to ketamine and to thiopental–nitrous oxide–halothane anesthesia, with two levels of preoperative information, were investigated in 48 young servicemen in a randomized, blind, prospective study. Ketamine produced a uniformly high incidence of illusions in both information groups, suggesting an intrinsic pharmacologic property of this drug. The combination of thiopental, nitrous oxide, and halothane also produced illusions, but their incidences were significantly… 

Psychomimetic reactions after low-dose ketamine infusion. Comparison with neuroleptanaesthesia.

Low-dose ketamine anaesthesia was compared with neuroleptanaesthesia, in respect of immediate and longer-term psychomimetic reactions, in 40 female patients undergoing elective gynaecological

Emergence phenomena after ketamine anaesthesia: the influence of music

Although the addition of music with ketamine anaesthesia increases the incidence of emergence phenomena the quality of wakening is pleasant and more acceptable to patients.

The effect of post-anaesthetic dreaming on patient acceptance of ketamine anaesthesia: A comparison with thiopentone-nitrous oxide anaesthesia

  • M. Krestow
  • Medicine, Psychology
    Canadian Anaesthetists' Society journal
  • 1974
The results confirm previous reports of a high incidence of dreaming and illusions after ketamine anaesthesia, and were intensely colourful, highly impressive, of abstract or concrete content, and frequently unpleasantly disturbing to the patient.

Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.

These data indicate that N-methyl-D-aspartate antagonists produce a broad range of symptoms, behaviors, and cognitive deficits that resemble aspects of endogenous psychoses, particularly schizophrenia and dissociative states.

Uneventful total intravenous anaesthesia with ketamine for schizophrenic surgical patients.

It is concluded that ketamine when combined with droperidol and fentanyl is a satisfactory anaesthetic for patients with schizophrenia.

Microadministration of Ketamine During Labor and Delivery of Nigerian Women

  • O. Ayangade
  • Medicine
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
  • 1978
Carefully controlled intravenous administration of ketamine produced excellent analgesia and dissociative sleep in all patients in the active phase of labor and the auditory component was consistently intact in 82% of the cases.

The effect of music on ketamine induced emergence phenomena

The majority of patients in the study group (80%) expressed their willingness to have a similar anaesthetic in the future compared to 52% in the control group (p < 0.05).

A Comparison of Clinical and Psychological Effects of Fentanyl and Nalbuphine in Ambulatory Gynecologic Patients

Drug dosages, length of stay (LOS), and incidence of psychological side effects of fentanyl and nalbuphine were compared in a randomized, double-blind study using unpre-medicated female day-surgery patients undergoing diagnostic laparoscopy to identify groups that clinically resembled the fentanyl group in terms of dosing frequency and patients' self-ratings of postoperative analgesia.

Halothane and Diazepam Inhibit Ketamine‐induced c‐fos Expression in the Rat Cingulate Cortex

Halothane and diazepam inhibited ketamine‐induced c‐Fos expression in the cingulate and retrosplenial cortices, leaving the thalamus relatively unaffected.