A Comparison of Noninvasive Positive-Pressure Ventilation and Conventional Mechanical Ventilation in Patients with Acute Respiratory Failure

@article{Antonelli1998ACO,
  title={A Comparison of Noninvasive Positive-Pressure Ventilation and Conventional Mechanical Ventilation in Patients with Acute Respiratory Failure},
  author={Massimo Antonelli and Giorgio Conti and Monica Rocco and M. Bufi and Roberto Alberto De Blasi and Gabriella Vivino and Alessandro Gasparetto and Gianfranco Umberto Meduri},
  journal={The New England Journal of Medicine},
  year={1998},
  volume={339},
  pages={429-435}
}
Background and Methods The role of noninvasive positive-pressure ventilation delivered through a face mask in patients with acute respiratory failure is uncertain. We conducted a prospective, randomized trial of noninvasive positive-pressure ventilation as compared with endotracheal intubation with conventional mechanical ventilation in 64 patients with hypoxemic acute respiratory failure who required mechanical ventilation. Results Within the first hour of ventilation, 20 of 32 patients (62… 
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