A Comparison of Methods To Enhance Protein Detection of Lipoproteins by Mass Spectrometry.


We sought to develop a new method to more efficiently analyze lipid-bound proteins by mass spectrometry using a combination of a lipid removal agent (LRA) that selectively targets lipid-bound proteins and a mass spectrometry compatible detergent, anionic acid labile surfactant (AALS), that is capable of eluting proteins off the LRA. This method was compared… (More)
DOI: 10.1021/acs.jproteome.5b00270


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