A Comparison of Fosinopril and Hydrochlorothiazide with Nifedipine SR in Patients with Mild to Moderate Hypertension

@article{Saini1997ACO,
  title={A Comparison of Fosinopril and Hydrochlorothiazide with Nifedipine SR in Patients with Mild to Moderate Hypertension},
  author={R. Saini and Francis R. Plat and J. Boussac},
  journal={Clinical Drug Investigation},
  year={1997},
  volume={14},
  pages={260-267}
}
  • R. Saini, Francis R. Plat, J. Boussac
  • Published 1997
  • Medicine
  • Clinical Drug Investigation
  • SummaryThis study compared the antihypertensive effects of a once-daily fosinopril/hydrochlorothiazide (FOS/HCTZ) combination (FOS 10 to 20 mg/HCTZ 12.5mg once daily) with that of twice-daily slow-release nifedipine (20mg) [NIF-SR] in patients with mild to moderate essential hypertension [seated diastolic blood pressure (SeDBP) of 95 to 110mm Hg]. A total of 164 patients were randomised to double-blind treatment (FOS/HCTZ, 80 patients; NIF-SR, 84 patients). At week 8, the percentage of patients… CONTINUE READING
    2 Citations
    Management of hypertension: the role of combination therapy.
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