A Comparative Study of Vertebrate Corneal Structure: The Evolution of a Refractive Lens.

@article{Winkler2015ACS,
  title={A Comparative Study of Vertebrate Corneal Structure: The Evolution of a Refractive Lens.},
  author={Moritz Winkler and Golroxan Shoa and Stephanie T Tran and Yilu Xie and Sarah Thomasy and VijayKrishna Raghunathan and Christopher John Murphy and Donald J. Brown and James V. Jester},
  journal={Investigative ophthalmology & visual science},
  year={2015},
  volume={56 4},
  pages={2764-72}
}
PURPOSE Although corneal curvature plays an important role in determining the refractive power of the vertebrate eye, the mechanisms controlling corneal shape remain largely unknown. To address this question, we performed a comparative study of vertebrate corneal structure to identify potential evolutionarily based changes that correlate with the development of a corneal refractive lens. METHODS Nonlinear optical (NLO) imaging of second-harmonic-generated (SHG) signals was used to image… CONTINUE READING