A Comparative Study of Transmembrane Diffusion and Permeation of Ibuprofen across Synthetic Membranes Using Franz Diffusion Cells

@inproceedings{Ng2010ACS,
  title={A Comparative Study of Transmembrane Diffusion and Permeation of Ibuprofen across Synthetic Membranes Using Franz Diffusion Cells},
  author={Shiow-Fern Ng and Jennifer J. Rouse and Dominic Sanderson and Gillian M. Eccleston},
  booktitle={Pharmaceutics},
  year={2010}
}
Synthetic membranes used in Franz diffusion cells for topical formulation quality assessment should provide least resistance to drug diffusion. In this study, the diffusion rates of ibuprofen across thirteen membranes were determined using Franz diffusion cells. Correlation of the membrane thickness, pore size and MWCO with drug fluxes was also made. The… CONTINUE READING