A Comparative Study of Techniques for Differential Expression Analysis on RNA-Seq Data

@inproceedings{Zhang2014ACS,
  title={A Comparative Study of Techniques for Differential Expression Analysis on RNA-Seq Data},
  author={Zong Hong Zhang and Dhanisha J. Jhaveri and Vikki M. Marshall and Denis C. Bauer and Janette Edson and R. Karthick Narayanan and Gregory J. Robinson and Andreas E. Lundberg and Perry F. Bartlett and Naomi R Wray and Qiongyi Zhao},
  booktitle={PloS one},
  year={2014}
}
Recent advances in next-generation sequencing technology allow high-throughput cDNA sequencing (RNA-Seq) to be widely applied in transcriptomic studies, in particular for detecting differentially expressed genes between groups. Many software packages have been developed for the identification of differentially expressed genes (DEGs) between treatment groups based on RNA-Seq data. However, there is a lack of consensus on how to approach an optimal study design and choice of suitable software for… CONTINUE READING
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