• Published 2007

A Common 8 q 24 Variant in Prostate and Breast Cancer from a Large Nested Case-Control Study

@inproceedings{Schumacher2007AC8,
  title={A Common 8 q 24 Variant in Prostate and Breast Cancer from a Large Nested Case-Control Study},
  author={Fredrick R. Schumacher and Heather Spencer Feigelson and David G. Cox and Christopher A. Haiman and Demetrius Albanes and Julie E. Buring and Eugenia E. Calle and Stephen J. Chanock and Graham A. Colditz and W Ryan Diver and Alison M. Dunning and Matthew L. Freedman and J. Michael Gaziano and Edward L. Giovannucci and Sue E. Hankinson and Richard B Hayes and Brian E. Henderson and Robert Nathaniel Hoover and Rudolf Kaaks and Timothy J Key and Laurence N. Kolonel and Peter Kraft and Loic Le Marchand and Jing Ma and Malcolm C. Pike and Elio Riboli and Meir J. Stampfer and Daniel O. Stram and Gilles Thomas and Michael J. Thun and Ruth C Travis and Jarmo R Virtamo and Gerald L. Andriole and Edward P. Gelmann and Walter C Willett and David J. Hunter},
  year={2007}
}
Two recent studies independently identified polymorphisms in the 8q24 region, including a single nucleotide polymorphism (rs1447295), strongly associated with prostate cancer risk. Here, we replicate the overall association in a large nested case-control study from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium using 6,637 prostate cancer cases and 7,361 matched controls. We also examine whether this polymorphism is associated with breast cancer among 2,604 Caucasian… CONTINUE READING

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Confirmation study of prostate cancer risk variants at 8q24 in African Americans identifies a novel risk locus.

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Genetic variants and family history predict prostate cancer similar to prostate-specific antigen.

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