A Commentary on microRNA-141 confers resistance to cisplatin-induced apoptosis by targeting YAP1 in human esophageal squamous cell carcinoma


Although chemotherapy has been widely used in treatment of cancer, drug resistance of cancer cells is a major clinical obstacle to curative effect and leads to poor prognosis of the patient. Many genetic (anticancer drug-induced random mutation of gene) and epigenetic (alteration of gene function without mutation) mechanisms have been reported to be the… (More)
DOI: 10.1038/jhg.2011.26