A Command Chemical Triggers an Innate Behavior by Sequential Activation of Multiple Peptidergic Ensembles

  title={A Command Chemical Triggers an Innate Behavior by Sequential Activation of Multiple Peptidergic Ensembles},
  author={Young-Joon Kim and D. Z̆itn̆an and C. G. Galizia and K. Cho and M. Adams},
  journal={Current Biology},
  • Young-Joon Kim, D. Z̆itn̆an, +2 authors M. Adams
  • Published 2006
  • Biology, Medicine
  • Current Biology
  • BACKGROUND At the end of each molt, insects shed their old cuticle by performing the ecdysis sequence, an innate behavior consisting of three steps: pre-ecdysis, ecdysis, and postecdysis. Blood-borne ecdysis-triggering hormone (ETH) activates the behavioral sequence through direct actions on the central nervous system. RESULTS To elucidate neural substrates underlying the ecdysis sequence, we identified neurons expressing ETH receptors (ETHRs) in Drosophila. Distinct ensembles of ETHR neurons… CONTINUE READING
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