A Combined Screening Platform for HIV Treatment Failure and Resistance


BACKGROUND To develop a low cost method to screen for virologic failure of antiretroviral therapy (ART) and HIV-1 drug resistance, we performed a retrospective evaluation of a screening assay using serial dilutions of HIV-1 RNA-spiked blood plasma and samples from patients receiving >6 months of first-line ART. METHODS Serial dilution testing was used to… (More)
DOI: 10.1371/journal.pone.0035401


4 Figures and Tables