A Cohort Mortality Study among Titanium Dioxide Manufacturing Workers in the United States

@article{Fryzek2003ACM,
  title={A Cohort Mortality Study among Titanium Dioxide Manufacturing Workers in the United States},
  author={Jon P Fryzek and Bandana K Chadda and Donald E. Marano and Kenneth L. White and Sarah Schweitzer and Joseph K. Mclaughlin and William J. Blot},
  journal={Journal of Occupational and Environmental Medicine},
  year={2003},
  volume={45},
  pages={400-409}
}
Although titanium dioxide (TiO2) is generally regarded as a nontoxic mild pulmonary irritant, some laboratory studies have reported lung adenomas in rats exposed to high levels of TiO2. Limited data on health effects among humans exist. A retrospective cohort mortality study was conducted among 4241 TiO2 workers who were employed for at least 6 months, on or after January 1, 1960, at four TiO2 plants in the United States. Exposure categories, defined by plant, job title, and calendar years in… 

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